The 2022 annual report on the activities of the Prolinnova subregional platform in Eastern and Southern Africa highlights the achievements, challenges and perspectives at both subregional and Country Platform levels. The achievements include identifying, documenting and sharing local innovation processes (and local innovations), facilitating farmer-led participatory innovation development, capacity strengthening, networking and fundraising. It also brings the lessons learnt from implementing the activities in 2022 and the plans for 2023.